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What is HIFU and Sonablate HIFU?
Device Comparisons


HIFU Device for Prostate Cancer

Sonablate® 500


  Sonalbate 500 Alblatherm

TURP* Required?

*A TURP is an invasive surgical procedure with risk of complications, excessive blood loss, infection, painful urination and 4-6 weeks recovery.


Can treat up to a 40cc prostate without invasive surgery prior to HIFU


Requires a transurethral resection of the prostate (TURP) with prostates larger than 24cc

Image Quality

Real-time and reference images give immediate feedback for maximum performance.  Images are in 3D for better detail and easier planning

No 3D imaging available. 

Does not use reference images during treatment.

Nerve Detection

During treatment planning, blood flow around nerves is identified with color overlay on real-time images thus protecting nerves responsible for preserving potency

Not capable of identifying or monitoring blood flow through neurovascular bundles resulting in a higher statistical incidence of erectile dysfunction, reported as high as 66%

The Probe

Small probe may be positioned for optimal outcomes and controlled by physician for maximum patient comfort 

A larger diameter probe* is fixed on the treatment table and not directly controlled by the physician

Power Adjustment

Features dynamic power adjustment to compensate for tissue response to  the sound waves

Three pre-set power levels which can not be adjusted to tissue response


12mm lesions are so precise in the focal zone that the physician can pinpoint an area without damaging surrounding tissue

19-24mm lesions could miss some prostatic tissue and increase the chance for a recurrence of the cancer

Safety Features

Reflexivity Index Measure alerts physician to patient movement

Rectal wall monitoring

Sonachill system circulates chilled water to protect delicate tissue outside the focal zone

Energy display provides immediate feedback on effectiveness of treatment

External motion detection

Refrigerated / temperature controlled gel to keep rectal wall temperature down

No energy display to provide immediate feedback during HIFU on effectiveness.

Tissue Change Monitoring

Link to Tissue Change Monitoring detailed information.




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